Neuromine
The gateway to discovery.
Neuromine is a next-generation data repository for ALS and neurodegenerative disease research. It offers powerful tools to search, filter, visualize, and download deeply curated datasets across transcriptomics, epigenomics, proteomics, and whole genome sequencing, paired with clinical profiles and cell line availability. To learn more about registering and requesting data, follow the link below.
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About Neuromine
Neuromine is an open-access data repository and collaborative research platform dedicated to accelerating discoveries in ALS and related neurodegenerative diseases. Supported and maintained by the Answer ALS Foundation, Neuromine brings together rich multiomics and clinical datasets from leading ALS research initiatives, including Answer ALS and the ALS Therapy Development Institute (ALS TDI).
Through Neuromine, researchers can explore and analyze data on thousands of individuals living with ALS, including whole genome sequencing, epigenomics, transcriptomics, proteomics, clinical assessments, and more. Our goal is to foster interdisciplinary collaboration and expand understanding of ALS biology by making these data sets accessible, integrated, and user-friendly.
Data
Analysis
Discovery
The programs contributing data to Neuromine
Answer ALS has contributed multiomics and clinical datasets to Neuromine from one of the largest coordinated ALS research programs. It includes OMIC data and clinical data from over 1,000 participants to support broad, data-driven ALS discoveries.
The ALS Therapy Development Institute has partnered with Neuromine to share extensive longitudinal data from its ALS Research Collaborative (ARC) Study. Launched in 2014, ARC remains the longest-running natural history study of ALS worldwide.
Data at a glance
To learn more about the disease, we enrolled over 2,700 patients. Here is a small sampling of the data we collected.
Data by Program
Combined Data
Explore More
Longitude Prize on ALS
This global challenge aims to accelerate the development of breakthrough algorithms that can identify novel drug targets for ALS. Data for the competition is drawn from several leading ALS initiatives, including Answer ALS and the ALS Therapy Development Institute (ALS TDI), providing participants with access to richly detailed clinical and multi-omics datasets to drive innovation and discovery. The Longitude Prize on ALS is designed and delivered by Challenge Works, the global challenge prize experts, part of Nesta, the UK’s innovation agency for social good.
Data
Neuromine provides open access to multiomics and clinical data from leading ALS research initiatives, including Answer ALS and ALS TDI. Researchers can explore whole genome sequencing, RNA-seq, proteomics, and longitudinal clinical data through an intuitive, user-friendly platform.
Collaborative Work Space
Neuromine data is available on the ADDI Collaborative platform to support secure, cloud-based analysis by the global research community. This integration enables researchers to explore and work with ALS multiomics and clinical data alongside other curated datasets.
Tools
New data visualization tools such as heatmaps, boxplots, and PCA are becoming increasingly popular for exploring and presenting complex data insights in a more intuitive and interactive way. To explore the Neuromine tool suite to investigate your selected cohort data, go to the Data Search page and request access.
OnPoint Scientific
Program Director
Terri Thompson, Ph.D, PMP
terri@onpointsci.com
terri@answerals.org
EPAM Systems
